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MODERN STRATEGIES OF SURGICAL TREATMENT OF PATIENTS WITH PELVIC CANCEROMATOSIS CAUSED BY THE OVARIAN CANCER = СУЧАСНІ СТРАТЕГІЇ ХІРУРГІЧНОГО ЛІКУВАННЯ ХВОРИХ НА ТАЗОВИЙ КАНЦЕРОМАТОЗ, ЗУМОВЛЕНИЙ РАКОМ ЯЄЧНИКІВ

Authors: Rybin, A. I.; Kuznetsova, O. V.; Maximovsky, V. E.;

MODERN STRATEGIES OF SURGICAL TREATMENT OF PATIENTS WITH PELVIC CANCEROMATOSIS CAUSED BY THE OVARIAN CANCER = СУЧАСНІ СТРАТЕГІЇ ХІРУРГІЧНОГО ЛІКУВАННЯ ХВОРИХ НА ТАЗОВИЙ КАНЦЕРОМАТОЗ, ЗУМОВЛЕНИЙ РАКОМ ЯЄЧНИКІВ

Abstract

Rybin A. I., Kuznetsova O. V., Maximovsky V. E. MODERN STRATEGIES OF SURGICAL TREATMENT OF PATIENTS WITH PELVIC CANCEROMATOSIS CAUSED BY THE OVARIAN CANCER = СУЧАСНІ СТРАТЕГІЇ ХІРУРГІЧНОГО ЛІКУВАННЯ ХВОРИХ НА ТАЗОВИЙ КАНЦЕРОМАТОЗ, ЗУМОВЛЕНИЙ РАКОМ ЯЄЧНИКІВ. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2020;2(87):64-70. ISSN 0049-6804. DOI http://dx.doi.org/10.5281/zenodo.3967728 http://www.herald.com.ua УДК 618.11-006.6-085.28.036.8 DOI http://dx.doi.org/10.5281/zenodo.3967728 СУЧАСНІ СТРАТЕГІЇ ХІРУРГІЧНОГО ЛІКУВАННЯ ХВОРИХ НА ТАЗОВИЙ КАНЦЕРОМАТОЗ, ЗУМОВЛЕНИЙ РАКОМ ЯЄЧНИКІВ А. І. Рибін, О. В. Кузнецова, В. Є. Максимовський Одеський національний медичний університет Summary. Rybin A. I., Kuznetsova O. V., Maximovsky V. E. MODERN STRATEGIES OF SURGICAL TREATMENT OF PATIENTS WITH PELVIC CANCEROMATOSIS CAUSED BY THE OVARIAN CANCER. In the article the authors show their own experience with the technique of intraoperative intraperitoneal hipertermychnoyi himioperfuziyi (HIPEC) in patients with disseminated ovarian cancer. Based on analysis of 25 clinical cases, the authors note that the technique is innovative and effective. Having the many advantages of the method found no difference in the toxicity of the drugs between traditional and advanced ovarian cancer treatment method using HIPEC. The authors consider, that hyperthermia is one of the possible mechanisms for overcoming resistance to platinum. Key words: pelvic canceromatosis, ovarian cancer, treatment, optimization, intraoperative hypertermic intraperitoneal chemoperfusion. Реферат. Рыбин А. И., Кузнецова А. В., Максимовский В. Е.СОВРЕМЕННЫЕ СТРАТЕГИИ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ БОЛЬНЫХ ТАЗОВЫХ КАНЦЕРОМАТОЗА, ОБУСЛОВЛЕННЫХ РАКОМ ЯИЧНИКОВ. В статье представлен собственный опыт авторов по применению методики интраоперационной гипертермичнои интраперитонеальной химиоперфузии (HIPEC) у больных распространенным раком яичников. На основании анализа 25 клинических случаев авторы отмечают, что разработанная методика является инновационной и эффективной. На фоне многих преимуществ метода не было обнаружено различий в токсичности применяемых препаратов между традиционной терапией РЯ и усовершенствованной методике с применением HIPEC. Авторы полагают, что гипертермия является одним из возможных механизмов преодоления резистентности к платине. Ключевые слова:тазовый канцероматоз, рак яичников, лечение, оптимизация, интраоперационная гипертермична интраперитонеально химио

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