Abstract. Cross-border crime utilizes recent advanced systems to perform their illegal activities. Innovative sensory systems and specialized equipment are examples that were used for tracking of human and of various illicit materials. The increasing challenges that border personnel must resolve require the usage of recent technological advances as well. Thus, the utilization of pioneer technologies seems imperative to precede technologically organized crime. Towards this objective, the introduction of Unmanned Vehicles (UxV) and the advances of relevant sub-systems has created a new solution to fight cross-border crime. Utilizing a combination of UxVs enriched with enhanced detection capabilities comprises an effective solution. The chapter will introduce and present the capability of an autonomous navigation system by exploiting swarm intelligence principles towards simplifying the overall operation. Computer vision advances and semantically enrichment of the acquired information are incorporated to deliver cutting edge technologies. The described architecture and services can provide a complete solution for optimal border surveillance and increased situation awareness.