Public Hospital of dr. Koesnadi Bondowoso has grappled with numerous issues related to data and information pertinent to patients, employees, schedules, medical records, queues, medicines, maintenance, finance, the number and effectiveness of employees and rooms, and so forth. The problems found by the researcher at the research site included system quality, information quality, and service quality. This research was quantitative in nature, conducted at Public Health of dr. Koesnadi Bondowoso with 32 people as the population. Thirty persons were chosen as research subjects, determined by random sampling. The researcher conducted a simple analytical test. The research results indicated that the influence of system quality to users satisfaction was evident, evinced by t-value of 6,39. Information quality also exerted significant influence to users satisfaction, with t-value of 14,74. Likewise, service quality was also proven influential to users satisfaction, marked by t-value of 13,65. The result of modelling generated in this research was formulated fit with p-value = 1,000 value RMSEA = 0,000 Degree of Freedom value = 0 Chi-Square value = 0,00. The research has concluded that the 3 exogenous variables under investigation yielded impact to endogenous variable, as corroborated by t-value across three correlational tests > 1,96. Suggestions for the hospital pertain to developing hospital information system in manual fashion first, followed by implementation and evaluation. Afterward, integrated electronic system should come underway.