Carcinoid heart disease is rare, and it is one of the primary pathologies of tricuspid and pulmonary valve. We present a 42-year-old woman who presented to our cardiology clinic with recent peripheral lower limb edema and dyspnea. Cardiac auscultation revealed a tricuspid regurgitation murmur the reason why we did the transthoracic echocardiography that demonstrated a unique right sided valvular heart disease with a morphological aspect of carcinoid heart disease. The patient has a right exophthalmos in the clinical examination that was highly suggestive of a brain tumor. So we decided to admit her in the hospital for further work up.