Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin

We prepared these datasets associated with the paper “Genome-scale imaging of the 3D organization and transcriptional activity of chromatin” published in Cell: https://doi.org/10.1016/j.cell.2020.07.032. Please find detailed descriptions of individual data files in the README_August 2020.txt. We provide example codes to load and analyze these datasets in: https://github.com/ZhuangLab/Chromatin_Analysis_2020_cell. If you use these datasets, please cite our Cell paper.

{"references": ["Su et al., \"Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin\", Cell (2020), https://doi.org/10.1016/j.cell.2020.07.032"]}

This work is supported in part by the National Institutes of Health (to X.Z.). X.Z. is a Howard Hughes Medical Institute Investigator.

Related Organizations

Harvard University
United States

Keywords

3D Genome organization, Chromosome compartments, Multiplexed FISH, Chromosome conformation, Genome-scale imaging, Nuclear speckles, Transchromosomal interaction, Nuclear lamina, Topologically Associated Domains, MERFISH

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