The present research was conducted using multi-method techniques. The first phase was a qualitative exploration of the need for an assessment tool for screening deception in confession statements. The second phase used objective quantitative technique to investigate the efficacy and validity of Reality Monitoring technique; within indigenous settings, with reference to different professions. The sample of the study consisted of 30 professionals from 5 professions, namely lawyers, police officers, psychologists, journalists, Urdu language and English language experts. The results followed that police officers had the highest ability to detect deception in confession statements and that RM technique is viable for indigenous setting, after a few practical considerations.