Covid-19's entry into the country triggered a series of effects on the productive sectors and the economy. Social isolation brought uncertainty about the future and made people rethink their entire way of consuming (how much, where, how and why). This fact has been generating repercussions on sales and revenues for companies that had to seek new strategies to market their products and guarantee income for maintaining their businesses during and after the pandemic. The aim of this paper is to discuss these strategies through the limitations imposed by social isolation. Thus, a qualitative analysis was performed using bibliographic and documentary research to support the study. An above-average growth of new e-commerce users and the use of collaborative strategies between small business owners and large virtual retail chains was identified to help boost sales for both in this pandemic period. If the strategy remains advantageous, as has been shown so far, there is a strong tendency to maintain these collaborations in the post-pandemic period.