Lupus nephritis is an autoimmune disease caused by systemic lupus erythematous, the prevalence of SLE and the chances of developing lupus nephritis (LN) vary considerably between different regions of the world and different races and ethnicities, a number of factors like genetic, environmental and immunology lead to inflammation of kidneys which is identified by biopsy, it is classified into six types based on the level of tissue damage and it is treated by induction, maintenance, adjuvant therapy and biological therapy. Mostly immunosuppressants, antimalarials are used.