The purposes of this research article were to study factors causing stress in the age of globalization. This is a qualitative research. The researcher studied factors affecting stress from previous researches, articles, books and other related documents. The research results showed that the nature of organizations tends to create a stressful environment. Human beings are living in a competitive age that can cause stress anytime. People with a higher percentage of stress causing from work, finance, social conflict and family problems may not be satisfied with their job. Therefore, they may not feel happy working in their organization. People who are stressful may feel frustrated and burned out when they are facing problems that can lead to create stress. This may leave a negative impact to the organization itself. Among many factors, personal factors consisting of financial problem, time management, and family problem organizational factors consisting of task demands and role demand, workload, co-worker relationship, and environmental factors, are the main factors affecting stress in the age of globalization.Stress destroys the morale, good feeling, intention, willingness and inspiration of employees to work in the company.