Gestational trophoblastic disease (GTD) include a broad spectrum of diseases ranging from benign precancerous lesions, partial and complete hydatidiform mole, malignant lesions, invasive moles, choriocarcinoma and tumors of the implantation site [1]. The incidence of hydatidiform mole is 1 in 1000?2000 pregnancies. The molar tubal pregnancy is extremely rare with an incidence of approximately 1.5 per 1 000 000 births [2]. We related in our series 5 cases of a tubular hydatiform mole collected in Obstetrics and Gynecology Department 1 of the Teaching Hospital Hassan II, Fez - Morocco, for a period of 7 years from 2010 to 2017. Three patients report an infertility history, with one secondary to polycystic ovary syndrome. The patients were submitted to gynecological emergencies for bleeding with pelvic pain, and in whom the dosage of β-hCG was positive with variable rates, and whose pelvic ultrasound performed was in favor of adnexal images with effusion. The ruptured EP was evoked in four cases hence the indications for exploratory laparotomy. One laparoscopic salpingectomy was performed for an unruptured ampullary EP. Surgical exploration revealed aspect of a ruptured tubal pregnancy appearance with in one case a vesicle appearance, with non-retainable tubes indicating salpingectomies with postoperative course was uneventful. The histopathological study mentioned the diagnosis of tubal hydatiform mole. The molar biological monitoring was satisfactory in all five cases.