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This dataset contains summary statistics of imputed genome-wide association study (GWAS) for nonsyndromic cleft lip with or without cleft palate (nsCL/P). The GWAS contains 399 cases with nsCL/P and 1,318 controls of Central European descent, and includes 8,820,921 autosomal SNPs. Details on sample recruitment/characteristics and genotyping can be found in Mangold et al. 2010 (PMID: 20023658). Further details on imputation can be found in Ludwig et al. 2017 (PMID: 28087736), and information on data structure is provided in the Additional Notes.
Data contain summary statistics for 8,820,921 autosomal SNPs with info scores >=0.4. Header is as follows: chr_pos (i.e., hg19) rsid RA (i.e., risk allele) OA (i.e., other allele) cases_freq_RA controls_freq_RA pvalue info beta se(beta)
cleft palate, GWAS, orofacial cleft, cleft lip
cleft palate, GWAS, orofacial cleft, cleft lip
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