Purpose: Developmental dysplasia of the hip (DDH) is one of the most common musculoskeletal problems in infants.It is also known as congenital hip dysplasia, but actually this is a misnomer. It is a developmental disease.The early detection of DDH by Ultrasonography within the first sex week of babies life and treatment for hip dysplasia has a higher probability of success. Therefore, the present study aimed to raise the issue of cost-effectiveness included US as a screening tool in neonatal screening by measuring the prevalence of hip dysplasia. Methods: A cross- sectional study was conducted on 50infants to measure the prevalence of Developmental dysplasia of the hip among infants at Maternity & Children hospital (MCH) in Al-Madinah city by using the ultrasound. Results: According to the study design, 50 patients were included in the study; the majority of the patients (47%) on the age group of (More than two months to three months) with 1:2 male to female ratio.The percentage of infants with developmental dysplasia of the hip is 78 % among all infants and two third of infants with developmental dysplasia of the hip had unilateral dysplasia of the hip. Conclusion: This study identified a high prevalence of developmental dysplasia of the hip among infants at Maternity & Children Hospital (MCH) in Al-Madinah city. Developmental dysplasia of the hip among infants commonly affected female infants and frequently with unilateral hip dysplasia.