Epithelioid hemangioendothelioma is a rare, slowly unfavorable vascular tumor. It is considered to be a malignant tumor. Localization in the skin is very rare and often part of a multi-systemic disorder. It has the potential for local recurrence, lymph node metastasis and at a distance and its not frequently accompanied by death. We report the observation of a 57-years-old patient, who is presented with an epithelioid hemangioendothelioma of the left buttock with a 1-year follow-up without recurrence.