Introduction: Postoperative graft thrombosis remains a significant clinical challenge. Etiologies are often multifactorial and include patient demographics, natural history, comorbidity conditions, and technical issues associated with arterial reconstruction. Here we analyze conditions favoring successful reintervention following lower limb graft thrombosis. Material and Methods: This is an observational study done in twenty patients who underwent reintervention procedures for graft thrombosis. Indications for interventions were critical limb ischemia with rest pain / tissue loss and disabling claudication. Results: Out of these twenty patients, post intervention patency rates were 60% (12 cases) and limb salvage rate were 70% (14 cases). Early intervention, claudicants and older patients had better patency and limb salvage in this study. Conclusion: Thus conditions favoring successful reintervention following lower limb graft thrombosis were early intervention, claudicants and older patients.