Urethral meateal cancer is a rare condition. The average age of onset is between 50 to 60 years old. This tumor results in a variety of clinical signs, the cytology and histology of the urethral sample are indispensables. Its diagnosis is often late, certainly sometimes unknown. Imaging remains the reference examination to be requested for the extension assessment. The treatment is essentially surgical. We report the case of a 58-year-old woman with dysuria with general deterioration of the condition for 5 months. The physical examination revealed an edematous, indurated, painful urethral meatus on palpation. Magnetic resonance imaging shows an injury process centered on the urethral meatus without any sign of loco-regional extension. Urethrocystectomy with colpohysterectomy followed by Bricker-type urinary diversion was performed. Histopathological examination of the part revealed a well-differentiated urethral adenocarcinoma.