Controversies surrounding formocresol which is associated as great pulpotomy medicament has actually triggered the search for much better options. And in this review we discuss the anatomy, background knowledge and indications of pulpotomy, the gold medicament utilized in pulpotomy (formocresol) and highlight the effectiveness of calcium hydroxide as alternative medicament.This narrative review was performed using electronic medical databases; PubMed, Embase, and Google scholar, searched was targeting relevant studies concerned with Pulpotomy and the use of calcium hydroxide in primary teeth published up to the end of 2019.Many variables should be taken into consideration in picking the appropriate remedy such as scientific efficacy, cost, as well as sensitivity of positioning method. Formocresol Pulpotomy appreciates great medical as well as radiographic success rates, and is quiet a popular pulpotomy material regardless of the issues increased because of its toxicity, mutagenicity and carcinogenicity. Calcium hydroxide has actually been called into question as a pulpotomy remedy due to the incident of inner root resorption complying with pulpotomy. Nonetheless, it ought to be emphasized that calcium hydroxide provided inferior outcomes than formocresol in all of the research studies.