The basic aim of the study is to find the abnormal values of liver function tests in hepatitis patients who are receiving different therapies and medications. This cross sectional study was conducted at Midcity Hospital, Lahore during January 2019 to July 2019. The data was collected from both genders and the sample size is 100. Detailed history was taken from all patients with special reference to duration of hepatitis, mode of infection, previous history of jaundice, HBV or HCV infection. A thorough clinical examination was carried out and stigmata of chronic liver disease, hepatosplenomegaly, ascites, etc. if present were noted. The demographic values of patient group and control group shows a significant difference. The data suggest clearly that CD4 count decreases in abnormal liver function. The results shown the table 02 demonstrates the multiple comparison of ALT, AST and ALP level among different treatments and normal group. It is concluded that hepatitis directly increase the liver enzymes even after receiving medication and other therapies. But our results shows that those patients who receive glutathione treatment are less suffer from liver abnormalities as compared to other therapies.