The field of forensics in dentistry is a growing area of research in the recent times. Dental Radiographs are an important tool when it comes to identification of human remains when there is no other way to discern the identity of a missing person. This study aims to establish the use of Frontal Sinus for Gender Determination by using common Dental Radiographs and thus providing an uncomplicated option to decide sex from skeletal remains. Methodology: One hundred Digital Caldwell?s Radiographs of 50 Males and 50 Females were studied using AutoCAD 2004 software for right, left and total area. Results: ROC curve analysis,Pearson Correlation and Simple Regression Analysis were used as statistical tools. The mean right, left and total frontal sinus area of males was comparatively higher than females. Conclusion: It was concluded that AutoCAD method to measure frontal sinus area in radiographs is a reliable method and can be used for determination of gender