The study investigate the Barriers Associated with Breast Cancer Screening among Women of Child Bearing Age in Calabar Municipality, Cross River State, Nigeria. The sample for the study consisted of 400 respondents which were randomly selected from 70 EdimOtop, 106 IkotIshie and 147 IkotOmin from Calabar Municipality, Cross River State. Four specific objectives were developed as follows: (i) To identify the cultural barriers associated with breast cancer screening among women of child bearing age in Calabar Municipality. (ii) To ascertain the socioeconomic barriers associated with breast cancer screening among women of child bearing age in Calabar Municipality. (iii) To identify the health system barriers associated with breast cancer screening among women of child bearing age in Calabar Municipality. (iv) To ascertain the personal barriers associated with breast cancer screening among women of child bearing age in Calabar Municipality. This study supports the findings of Ahmad (2015) who reported that one fifth of Arabic mothers with poor knowledge stated that their culture depicted women who carry out breast cancer screening as promiscuous women.