In this study, the effect of Aqueous Extractors, Organic Solvent) Ethyl Ethanol) Hexane Alcohol) and the minor Hydroxylated represented by Adlumidine and Flavonoid of Chara sp. to words pupa of Aedes Albopticus. The results showed different effects for the extractors, which used in killing the Larvae. Hexane extractor has supremacy of LC50 and LC90 of mosquito Larvae reached 1000 and 3000 ppm respectively after 24 hours of treatment, and the rate of killing reached 65%, followed by Alcoholic Extractor with LC50 and LC90 reached 1000 and 4000 respectively, after 48 hours of treatment the rate of killing was 59.16%. Then Alkaloid Extractor with LC50 and LC90 reached 1200 and 6500 ppm after 48 hours of treatment, and the rate of killing was 53.33%. Finally, Flavonoid Extractor and Water Extractors are the least effective among the extractors used in killing ratio, which reached 35.05% and 5.16% respectively.