Psidium guajava (guava), a tropical plant is used as a food .In rural area it can be used as medicine due its medicinal properties. Guava is easily cultivated in India, so it reflects its usage in rural communities for treatment of different conditions. According to information of clinical trials on guava obtained from Cochrane Central Register of Controlled Trials and Clinical Trial. gov. Various medicinal properties of guava have been reported from the survey. It is very effective in various conditions like-1)Skin infection 2)Respiratory infection 3)Malaria 4)Oral or Dental infection 5)pain 6) Immunostimulant 7)Woman problems 8) Kidney problem 9)Malnutrition 10)Hypertension and CVS 11)Liver problem 12)diabetes 13)Fever 14) Cancer. Keywords: Psidium guajava , Guava, India, Multiple Activity.