End stage renal disease (ESRD) could affect many aspects of patient’s life including sleep quality. Severe sleep disorders if not detected and managed properly, may in turn exacerbate the patient’s condition and increase the mortality rate. Determining the sleep disorders rate, and to assess the severity of sleepiness among ESRD patients is an important issue. A cross-sectional study was conducted in renal dialysis unit at Al-Yarmook Teaching Hospital, in Baghdad, during a five months period. A sample of 150 ESRD patients with undergoing haemodialysis (HD) was collected. Face to face interview was carried-out with each participant, using a reliable and validated questionnaire. This questionnaire containing a nine-item -specific for sleep disorder scale, and eight items that reflect the presence and severity of a sleep disorder using the 24-score Epworth sleepiness scale (ESS). Beside that the socio demographic information was included. The prevalence of sleep disorder was 78.66%. About 30% had moderate to severe sleep disorder, 46% had mild sleep disorders while 24% of patients were normal. Three factors were found to be significantly increasing the risk of sleep disorders. Those were: old age ≥ 50 years (OR = 2.24 95% CI 1.04-4.82), single marital status (OR= 2.81, 95% CI 1.08-7.31), and presence of comorbidity, represented by type 2 diabetes mellitus (DM) (OR= 4.04, 95% CI 1.06-15.35) or both DM, and hypertension (OR = 3.23, 95% CI 1.15-9.09). Sleep disorders are very common among patients with ESRD undergoing HD. Old ages (50 years or over) single patients, and the presence of chronic comorbidity, especially DM, are independent risk factors for developing sleep disorders among HD patients.