MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract

descriptionPublicationkeyboard_double_arrow_right Article 03 Dec 2019 English Publisher:Springer Science and Business Media LLCJournal:Human Genetics, volume 139, pages 151-184 (issn: 0340-6717, eissn: 1432-1203,

Copyright policy )Funded by:NIH | OHSU Knight Cancer Instit..., NIH | POST TRANSCRIPTIONAL CONT..., NIH | OPHTHALMOLOGY CORE FACILI... +3 projects

Authors: Sandeep Aryal; Deepti Anand; Francisco G. Hernandez; Bailey A. T. Weatherbee; Hongzhan Huang; Ashok P. Reddy; Phillip A. Wilmarth; +2 Authors

doi: 10.1007/s00439-019-02095-5 , 10.5281/zenodo.3490729 , 10.5281/zenodo.3490730

pmid: 31797049

pmc: PMC6983357

MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract

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Abstract

The uploaded files are supplementary tables for a submitted manuscript in NAR Genomics and Bioinformatics journal Manuscript ID: NARGAB-2019-089 Manuscript title: MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract Authors: Aryal, Sandeep; Anand, Deepti; Hernandez, Francisco; Weatherbee, Bailey; Huang, Hongzhan; Reddy, Ashok; Wilmarth, Phillip; David, Larry; Lachke, Salil* *Corresponding author: Salil A. Lachke, Department of Biological Sciences, University of Delaware, 105 The Green, Delaware Avenue, 236 Wolf Hall, Newark, DE, USA, Tel.: (302) 831 3040; Fax: (302) 831 2281; E-mail: salil@udel.edu Grant support: Supported by National Institutes of Health (NIH) Grant R01 EY021505 to Dr. Salil A. Lachke Keywords: Lens, iSyTE, Proteome, Embryonic lens development, Protein profiling, Database

Related Organizations

University of Delaware
United States
Oregon Health & Science University
United States

Keywords

Proteome, Gene Expression Profiling, Computational Biology, Cataract, Mice, Inbred C57BL, Mice, Tandem Mass Spectrometry, Lens, Crystalline, Animals, Humans, Computer Simulation, Eye Proteins, Transcriptome, Biomarkers

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