The main objective of this research is to analyze the factors that influence the safety of Indonesian nurses working in Qatar. The population in this study were 58 nurses, while the sample taken was 43 respondents who were chosen at random sample. The validity test and the reliability test of the variable indicator questions using SmartPLS version 3.2 with the requirements to meet the outer model, while testing the hypothesis using testing the structural model (inner model) using the SmartPLS program version 3.2 The results showed that the variable indicator question items had met the criteria of validity and reliability. Test the validity of the loading factor, cross loading, AVE values indicate that the instrument is valid. Reliability tests that were tested using composite reliability and Cronbach\'s Alpha met the requirements. Furthermore, hypothesis testing using SmartPLS shows that the Occupational Safety and Health (OSH) knowledge of nurses has no effect on the work environment and the work safety of nurses. The nurse\'s OSH behavior has a positive and significant effect on the work environment and the work safety of nurses. The OSH culture of nurses has a positive and significant effect on the work environment and the work safety of nurses.