Supplementary Videos S1-S2 3D co-culture spheroid formation containing A498-ST cells Representative movies (S1, bright field and S2, fluorescence stained) recorded for 24 hours of an A498-ST 3D co-culture capturing the kinetic formation of a 3D spheroid. 3D co-cultures harbor 70% tumor cells (A498-ST, green), 20% fibroblasts (NHDFα, blue) and 10% endothelial cells (ECRF24, red). Scalebar represents 1000 µm.