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Article . 2017
License: CC BY
Data sources: Datacite
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Article . 2017
License: CC BY
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Frailty And Subclinical Atherosclerosis

Authors: Moatassem Salah Amer*1, Randa Abdel WahabReda Mabrouk2 , Omar Hussein Omar3, Tarekkhairy Abdel Dayem4, Samia Ahmed Abdul-Rahman5& Basma Kamel Abdel Aziz6;

Frailty And Subclinical Atherosclerosis

Abstract

Background: Frailty as well as atherosclerotic diseases are commonly prevalent among elderly subjects and usually share both complex pathway and risk factors. Hence it was important to study if there is an association between frailty and risk factors of atherosclerosisat its early stages (subclinical atherosclerosis) using the Ankle Brachial Index (ABI), carotid intima media thickness (CIMT) and Abdominal Aortic Diameter (AAD) as markers of subclinical atherosclerosis. Material and Methods: A cross-sectional study conducted on 90 elderly participants (60-year-old and above), free of cardiovascular symptoms. They were dividedaccording to modified Fried criteria into: non-frail, pre-frail and frail groupsand they were subjected to comprehensive geriatric assessment, calculation of ABI, and radiological investigations including: carotid duplex to measure CIMT and abdominal ultrasound to measure AAD. Results: The study showed that frail participants had lower mean ABI value than non-frail group. Frail and pre-frail participants had higher maximum CIMT values than non-frail group. The mean AAD increased from 19.88 mm in the non-frail to 20.40 mm in the pre-frail group and 21.17 mm in the frail group, but this difference still not reaching a statistical significance. Conclusion: The study concluded that frailty is associated with subclinical atherosclerosis.

Keywords

Frailty, Atherosclerosis, Ankle Brachial Index, Carotid Intima media thickness, Abdominal Aortic diameter.

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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