Migraine is a benign and recurrent syndrome of headache, nausea, vomiting and other symptoms of neurological dysfunctions in varying admixtures. It is as one of the diseases where cause is exactly not known. Migraine, the second most common reason for cerebral pain, afflicts around 15% of women and 6% of men. With the disease afflicting majority of the people in their prime age i.e. from second decade to fifth decade, it is affecting their professional and social life, hampering their health. The various treatment modules comprises of non-pharmacological treatment such as identification of triggers, meditation, relaxation training, psychotherapy etc. and pharmacotherapy as abortive and preventive therapy. Ardhavabhedaka can be scientifically correlated with Migraine due to its cardinal feature ?half sided headache? and also due to its paroxysmal nature. All the three doshas are involved in the pathogenesis of the Ardhavabhedaka with the predominance of Vata or Vatakapha. The disease may not be fatal but if not managed properly then it may damage eyesight or hearing. Ayurveda emphasizes various treatment modalities for Ardhavabhedaka which includes both shamana, shodhana. asthapana and anuvasanabasti to be effective in the management ofArdhavabhedaka. This patient was treated with LaghuSootshekhar Rasa, NarikelLavana, GodantiBhasma and PathyadiKwathare found to be efficacious in the whole symptom of Migraine (Ardhavabhedaka).