In the situation of increasing range and strength of medicines, safety of medicines is the key parameter along with therapeutic efficacy for favorable outcome of any drug. India is now a preferred clinical trials port of call for drug entities to be launched. By viewing the increasing incidences, dug related mortality rate, proper identification of ADR’s, reporting, evaluation and understanding of adverse drug reaction leads to the development of pharmacovigilance. Pharmacovigilance is branch of pharmacological science censorious to effective clinical practices and public health with immense ability of growth. This article summarizes aims, objectives and methods of pharmacovigilance and characterization of ADR’s.1