This is the artifact submitted alongside the Seq paper to OOPSLA 2019, which consists of a VM containing an alpha build of Seq, as well as a usage guide. Seq is a programming language for computational genomics and bioinformatics. With a Python-compatible syntax and a host of domain-specific features and optimizations, Seq makes writing high-performance genomics software as easy as writing Python code, and achieves performance comparable to (and in many cases better than) C/C++. http://seq.csail.mit.edu