Background: Cosmetic can defined as superficial measures to make something appear better, more attractive, or more impressive. these measures include products, medication and surgeries,etc. Medication use cosmetically is one of the prevalent practice especially among female and may lead to several health problems ranging from minor to major that may lead a significant impact medically, psychologically, economically and socially on the patient, family , society and the country. lack of knowledge about the potential risk and complication of this practice was one of the main reasons for us to start this project. Objective: To Assess medications use for cosmetic purposes in females from 18 to 25 years old in Sudair Area 2017 Methods: Cross sectional study to Assess medications use for cosmetic purposes in females from 18 to 25 years old in Sudair Area 2017. Setting This study was conducted Sudair Area , 2017 Participants A population-based sample size of 300 female in the age group of 18 -25 years was selected by systematic sampling method Results: Result shows that the majority of participants (54%) were using some medication for cosmetic purpose. Where (41.3%) of participants who are using medication for cosmetic purpose were in 21-23 years age group. (53.3%) of participant were using Isoretinion for cosmetic purpose while (22%) of them were using corticosteroid. Conclusion: High prevalence Of medication use for cosmetic purpose as a common practice especially among female. Highlights a measure need to be taken to increase awareness of the population about these prevalent practices.