Bhagandara is one of Ashtomahagada described by Acharya Sushruta as it is difficult to cure. Bhagandara is a track lined by unhealthy granulation tissue and can be correlated with Fistula in Ano. It is a disease that has plagued humanity since time immemorial. The anal fistula most common illness affecting the male gender globally. For the management of Bhagandara (Fistula in ano) number of surgical treatment modalities are available but their limitations and complications are developed hence it is still big challenge to surgeons to treat especially of complex and recurrent fistula in ano (Bhagandara) hence it is notorious disease. In Ayurveda Sushruta has described various types of treatment modalities like Chedana karma, Ksharsutra therapy, and in modern science Fistulectomy, Fistulotomy is the choice of treatment. Fistula is a chronic state of Anorectal infection, the main concern of fistula in ano is duration of treatment and recurrence. Hence in Ayurveda and modern science many technique develops to reduce these complications, like Interception of Fistulous Tract with Application of Ksharsutra (IFTAK), Ligation of Intersphincteric Fistula Tract (LIFT), Seton placement etc. are the recent advance treatment modalities available for management of Bhagandara.