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ZENODO
Software . 2019
License: CC BY
Data sources: Datacite
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ZENODO
Software . 2019
License: CC BY
Data sources: ZENODO
Claim

DNAmArray: Streamlined workflow for the quality control, normalization, and analysis of Illumina methylation array data

integration_instructionsResearch softwarekeyboard_double_arrow_right Software 11 Jul 2019Publisher:ZenodoFunded by:EC | BBMRI
Authors: Sinke, Lucy; van Iterson, Maarten; Cats, Davy; Slieker, Roderick; Heijmans, Bas;

doi: 10.5281/zenodo.3355292

DNAmArray: Streamlined workflow for the quality control, normalization, and analysis of Illumina methylation array data

Abstract

Here we provide a complete workflow for the preprocessing and analysis of DNA methylation array data. The workflow combines best practices in the field with in-house developed methodology, and is geared towards large-scale studies, including Epigenome-wide Association Studies (EWAS). Its development was informed by our research analysing BIOS consortium data, which contains multiomics measures from 6 Dutch biobanks comprising ~4000 individuals.

Related Organizations
Keywords

450k array, Illumina Human DNA Methylation BeadChip, 850k array

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 5
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Top 10%
Average
Average
Funded by
Related to Research communities
Netherlands Research Portal
EGI : advanced computing for research