Peripheral Arterial Disease (PAD) is a common disease experienced by more than 202 million people worldwide, with an incidence that is directly proportional with age. PAD is a disorder of blood supplyto the extremities mainly caused by obstruction, which can primarily be atherosclerosis, thrombosis, embolism, vasculitis, or fibro muscular dysplasia. Studies showed that a high number of patients with Chronic Kidney Disease also had PAD. CKD increases the risk cardiovascular diseases which can increase the risk of PAD. This is a cross sectional study analyzing patients with End Stage Renal Failure who underwent hemodialysis and fulfilled the inclusion and exclusion criteria. The patients diagnosed with CKD had several risk factors such as Diabetes Mellitus, Hypertension, Dyslipidemia, Obesity, and Smoking. These risk factors are similar to those of cardiovascular diseases. This study was conducted at the Hemodialysis Room of Haji Adam Malik General Hospital during the months of May to August 2018.There is a significance in every criterion between the risk of cardiovascular disease and PAD, with every risk factor having the p value of less than 0.05.This study showed a significant correlation between PAD in patients with CKD that had the cardiovascular of risk factors.