Indonesia is ranked 3rd out of 8 countries with a high burden of Tuberculosis in the world. West Java Province became the first place in Indonesia with the number of new cases of Tuberculosis in children with 14.96% of the total Tuberculosis sufferers in West Java. The proportion of Tuberculosis in children cases at Sumedang District in 2018 amounted to 214 cases (12.7%) of the total Tuberculosis cases (1693 cases). Tuberculosis in children should be a priority as in overcoming it, because children are the future of the nation that must be healthy, grow and develop optimally. Research about the risk factors for the incidence of Tuberculosis in children at Sumedang District has never been conducted. Identification of risk factors will be very useful for planning an appropriate Tuberculosis prevention interventions in Sumedang District. The purpose of this study was to analyze the characteristics and risk factors for the incidence of Tuberculosis in children at Sumedang District. The research method used was analytic observational with a case control study design with 45 cases and 45 controls. The results of bivariate analysis by implementing Chi Square test showed that the variables related were; ventilation area (p = 0.011, OR = 3.4) home lighting (p = 0.020, OR = 3.0), cigarette exposure (p = 0.042, OR = 4, 5), contact history (p = 0,000 OR = 8,6), maternal behavior (p = 0,029, OR = 3.0) with the results of multivariate analysis by implementing logistic regression test showing the contact history (p = 0,000, OR = 12,0) and ventilation area (p = 0,003, OR = 5,4). Conclusion: Ventilation area, home lighting, cigarette exposure, contact history and maternal behavior were the risk factors for the incidence of Tuberculosis in children at Sumedang District with the dominant factor are contact history and ventilation area.