This dataset contains all patch clamp, confocal and mass spectrometry datasets of our publication 'Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium', published in BMC Biology. The data for each figure (fig 1-7) and supplementary figure (1-3) has been collected to an individual zipped folder. For additional information, please contact the corresponding author (Soile Nymark).