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DIFFUSE ALVEOLAR HEMORRHAGE : A RARE COMPLICATION OF METHIMAZOLE THERAPY

Authors: Dr. Nidhi Bhat, MD;

DIFFUSE ALVEOLAR HEMORRHAGE : A RARE COMPLICATION OF METHIMAZOLE THERAPY

Abstract

Diffuse alveolar hemorrhage (DAH) is a rare & catastrophic complication of methimazole therapy. The author reports a 44-year old female with a history of hyperthyroidism & poor compliance to methimazole therapy, presented to the emergency department with complaints of massive hemoptysis & respiratory failure. Further investigation lead to the diagnosis of thyroid storm & she was started on methimazole, steroids & beta blockers. Despite appropriate treatment, the patient’s condition worsened. Further workup revealed that the patient had DAH. After ruling out other etiologies, methimazole induced DAH was postulated & the patient was switched to propylthiouracil & steroids. Repeat bronchoscopy did not reveal any additional signs of DAH & the patient made a good recovery.

Keywords

Diffuse alveolar hemorrhage, Methimazole, ANCA negative vasculitis

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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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