The US Institute of Medicine committee in their 2011 report⁠ on Adverse Effects of Vaccines: Evidence and Causality wrote: "The committee concluded the evidence convincingly supports 14 spe-cific vaccine–adverse event relationships. In all but one of these relation-ships, the conclusion was based on strong mechanistic evidence with the epidemiologic evidence rated as either limited confidence or insufficient." So in an overwhelming 93% (13 of 14) cases, mechanistic studies provided convincing evidence and epidemiological studies failed to do so. Epidemiological studies are weak, have numerous sources of confounding and offer little value. Epidemiological study results are misinterpreted leading to type II errors. ⁠ Basically, with all vaccines containing uncontrolled levels of numerous non-target proteins (food, animal, fungal. viral/bacterial, etc), epidemiological studies are useless. The results cannot be replicated. These studies are ripe for cherry-picking. There is no science in vaccine safety related epidemiological studies. The focus must be on mechanistic studies and evidence.