In this paper, the TODIM method is used to solve the multi-attribute decision-making problem with unknown attribute weight in venture capital, and the decision information is given in the form of single-valued neutrosophic numbers. In order to consider the objectivity and subjectivity of decision-making problems reasonably, the optimal weight is obtained by combining subjective weights and objective weights. Subjective weights are given directly by decision makers. Objective weights are obtained by establishing a weight optimization model with known decision information, then this method will compare with entropy weight method. These simulation results also validate the effectiveness and reasonableness of this proposed method.