Raw diffraction images of the first bromodomain of human BRD4 in complex with (+)-JD1, an Organometallic BET Bromodomain Inhibitor. The final structure is deposited in the Protein Data Bank under accession code 6SE4. The structure is part of the following publication: Hassell-Hart, S., Runcie, A., Krojer, T., Doyle, J., Lineham, E., Ocasio, C.A., Neto, B.A.D., Fedorov, O., Marsh, G., Maple, H., et al. (2019). Synthesis and Biological Investigation of (+)-JD1, an Organometallic BET Bromodomain Inhibitor. Organometallics. doi: 10.1021/acs.organomet.9b00750. Additional information: dataset: BRD4A-JD1_i03 beamline: Diamond Light Source I03 visit: mx19301-7 date: 25-11-2018 Flux: 2.03e+11 Ω Start: 0.0° Ω Osc: 0.15° Ω Overlap: 0° No. Images: 1200 Resolution: 1.50Å Wavelength: 0.9762Å Exposure: 0.030s Transmission: 100.00% Beamsize: 80x20μm datasets: BRD4A-JD1_i04 beamline: Diamond Light Source I04 visit: mx19301-9 date: 08-12-2018 Flux: 6.62e+11 Ω Start: 0.0° Ω Osc: 0.50° Ω Overlap: 0° No. Images: 720 Resolution: 2.30Å Wavelength: 1.7384Å Exposure: 0.050s Transmission: 100.00% Beamsize: 32x20μm Additionally, a cif file containing refinement restraints and a png file for the ligand JD1 is included.