Tree sequences inferred for the 1000 Genomes phase 3 autosomes using tsinfer version 0.1.4 and compressed using tszip. Tree sequences can be decompressed as follows: $ tsunzip 1kg_chr1.trees.tsz Once decompressed, trees files can be loaded and processed using tskit. import tskit ts = tskit.load("1kg_chr1.trees") # ts is an instance of tskit.TreeSequence print("Chromosome 1 contains {} trees".format(ts.num_trees)) Metadata associated with individuals and populations was derived from the original source and converted to JSON form. For example, to access individual metadata we can use: import tskit import json ts = tskit.load("1kg_chr1.trees") ind = ts.individual(0) metadata_dict = json.loads(ind.metadata) The metadata_dict variable will now contain all the metadata for the individual with ID 0 as a dictionary. Metadata associated with populations can be found in a similar way. Population IDs are associated with individuals via their constituent nodes. For example, pop_metadata = [json.loads(pop.metadata) for pop in ts.populations()] ind_node = ts.node(ind.nodes[0]) ind_pop_metadata = pop_metadata[ind_node.population] After this, the ind_pop_metadata variable will contain the population level metadata for individual ID 0. The full data pipeline used to generate these tree sequences and associated metadata is available on GitHub.

{"references": ["Kelleher et al 2019, Inferring the ancestry of everyone. https://doi.org/10.1101/458067"]}

AWW and CF would like to thank the Rhodes Trust for their generous support.