Plant of immortality is the term used by Egyptians to describe aloe vera since it can be vital and effloresce even in truancy of soil. Aloe vera is the primeval medicinal plant ever known and the most applied medicinal plant worldwide. Its apposite in dentistry is reviewed below par. Many researchers have gathered interest in regarding the use of this plant as antiseptic, anti inflammatory, antiviral and antifungal. Aloe vera is also non allergic and good in boosting up the immune system. Aloe vera is gaining great popularity in dentistry as it is completely natural and thus reported to have no side effects. This article is steered to concisely review the history of use of aloe vera in medicine, its active ingredients, mechanism of action, clinical uses related to dentistry and its possible corollary.