Crystal structure of the thermostabilized human ETB receptor in complex with peptide inverse agonist IRL2500 (PDB code: 6K1Q). Small-wedge (5-10°/crystal) datasets collected from loop-harvested microcrystals using EIGER X 9M detector at a wavelength of 1 Å on BL32XU, SPring-8. Beam size was around 10×10 µm2 and oscillation step was 0.1°. The crystals belonged to space group I422 with unit cell parameters a=b~110, c~292 Å. In total 441 datasets were collected, and of these 428 datasets were indexed and integrated using XDS with KAMO pipeline. 88 integrated results were manually selected and finally 58 were merged at 2.6 Å resolution after CC-based clustering and outlier rejection by KAMO in the published result (Nagiri et al. Communications Biology, 2019).