Climatic changes and intensive industrialization have contributed to increasing the risk of damage of cultural heritage (CH) artefacts. On the other hand, small and medium-sized museums, as well as small CH sites struggle to fulfil international recommendations for protection and conservation, due to budget limitations. The constantly increasing potential of IoT-enabled devices and the establishment of cloud technologies as an enabling framework can help address this issue. In this chapter, the authors present an internet of everything (IoE) architecture, empowered by an easy-to-deploy cloud framework for the protection of CH. Particular use cases from CH sites are presented, as these have been identified in H2020 STORM project for safeguarding cultural heritage through technical and organizational resources management.