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Article . 2019
License: CC BY
Data sources: Datacite
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Article . 2019
License: CC BY
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https://zenodo.org/record/2650...
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Re-Purification of ALK2 for crystallisation with different compounds from M4K.

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 24 Apr 2019 English Publisher:Zenodo
Authors: Williams, E.P.; Bullock, A.N.;

doi: 10.5281/zenodo.2650203 , 10.5281/zenodo.2650202

Re-Purification of ALK2 for crystallisation with different compounds from M4K.

Abstract

Funding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.

Cleaning up of a frozen purified sample of ALK2/ACVR1 by gel filtration after thawing for use in co-crystallisation trials with five M4K compounds (M4K2163, M4K2143, M4K2192, M4K2207 and M4K2194). You can read more about it on Open Lab Notebooks.

Keywords

M4K Pharma, ALK2, Crystallisation, ACVR1A

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