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Conference object . 2019
License: CC BY
Data sources: Datacite
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Conference object . 2019
License: CC BY
Data sources: Datacite
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Other literature type . 2019
License: CC BY
Data sources: ZENODO
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In-silico SMILES-based toxicity prediction of fluorescent dye (Rh-B)

descriptionPublicationkeyboard_double_arrow_right Conference object , Other literature type 07 Apr 2019 English Publisher:Zenodo
Authors: Arulanandam Charli Deepak; Dahms Hans-Uwe;

doi: 10.5281/zenodo.2631896 , 10.5281/zenodo.2631897

In-silico SMILES-based toxicity prediction of fluorescent dye (Rh-B)

Abstract

The aim of this study was to investigate the toxicity of Rhodamine B (Rh-B) via computational tools. Rh-B is a fluorescent organic dye and it has much importance because of its photo-physical properties. The ‘International Agency for Research on Cancer’ classified Rh-B in the risk category for human cancer (CAS No. 81-88-9)This illegally used food colorant was here assessed for its toxicity via computational tools. For this assessment we used LAZAR Toxicity Predictions, PROTOX and pkCSM to explore about the pharmacokinetic and toxicological properties of Rh-B. We simulated Rh-B structure based on SMILES build by ACD/ChemSketch. This assessment shows that Rh-B provides carcinogenic, hepatotoxic risk for humans with a maximum recommended tolerated dose of 0.423 log(mg/kg/day).

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
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