Biostatistics is well recognized as an essential tool in medical research, clinical research and health research. Biostatistics is the branch of statistics applied to biological areas or medical sciences or medical research. Biostatistics not only covers the health, medicine, and nutrition but also covers the agriculture, genetics, biology, biochemistry, demography, epidemiology, anthropology and many others. Biostatistics helps to evaluate many life and death issues in medicine. The aim of this article is to educate the medical residents about the applications of biostatistics so that the proper and accurate conclusions may be drawn from the study.