Traditionally used metallic implants for fracture stabilisation even though have potential capability for fracture healing have been associated with significant disadvantages like patient incompliance and implant loosening leading to mal union, non-union and dis-union. Veterinary orthopaedics during the last decade has visualised a significant development with respect to use of biomaterials particularly in the field of fracture treatment and stabilisation. A large variety of biomaterials are available in the form of bone grafts and bone substitutes for commercial use to treat significant bone defects due to trauma and to enhance the rate of fracture healing. The present article aims to give an insight into the various bone grafts and bone substitutes available, their potential uses, applications, advantages and limitations in veterinary field.