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Elements of RNA, its Techniques and Applications

Authors: Mitra, Manu;

Elements of RNA, its Techniques and Applications

Abstract

{"references": ["Mallawaarachchi, V. (2017, August 18). Starting off in Bioinformatics? RNA Transcription and Translation. Retrieved from https://towardsdatascience.com/starting-off-in-bioinformatics-rna-transcription-and-translation-aaa7a91db031", "MacKenzie, R. J. (2018, January 24). DNA vs. RNA ? 5 Key Differences and Comparison. Retrieved from https://www.technologynetworks.com/genomics/lists/what-are-the-key-differences-between-dna-and-rna-296719", "Alexis B\u00e9d\u00e9carrats, Shanping Chen, Kaycey Pearce, Diancai Cai, David L. Glanzman. RNA from Trained Aplysia Can Induce an Epigenetic Engram for Long-Term Sensitization in Untrained Aplysia. eneuro, 2018; ENEURO.0038-18.2018 DOI: 10.1523/ENEURO.0038-18.2018", "University of California - Los Angeles. (2018, May 14). Biologists 'transfer' a memory through RNA injection: Research in marine snails could lead to new treatments to restore memories and alter traumatic ones. ScienceDaily. Retrieved November 15, 2018 from www.sciencedaily.com/releases/2018/05/180514151920.htm", "Brenda M. Calderon, Graeme L. Conn. A human cellular noncoding RNA activates the antiviral protein 2\u2032\u20135\u2032-oligoadenylate synthetase 1. Journal of Biological Chemistry, 2018; 293 (41): 16115 DOI: 10.1074/jbc.RA118.004747", "American Society for Biochemistry and Molecular Biology. (2018, October 12). An RNA key that unlocks innate immunity. ScienceDaily. Retrieved November 15, 2018 from www.sciencedaily.com/releases/2018/10/181012151633.htm", "See-Chuan Yam, Sharifuddin Md. Zain, Vannajan Sanghiran Lee, Khian-Hooi Chew. Correlation between polar surface area and bioferroelectricity in DNA and RNA nucleobases. The European Physical Journal E, 2018; 41 (7) DOI: 10.1140/epje/i2018-11696-5", "Springer. (2018, August 21). Switching DNA and RNA on and off. ScienceDaily. Retrieved November 15, 2018 from www.sciencedaily.com/releases/2018/08/180821111935.htm", "Alexander A. Green, Jongmin Kim, Duo Ma, Pamela A. Silver, James J. Collins, Peng Yin. Complex cellular logic computation using ribocomputing devices. Nature, 2017; DOI: 10.1038/nature23271", "Arizona State University. (2017, July 26). Living computers: RNA circuits transform cells into nanodevices. ScienceDaily. Retrieved November 15, 2018 from www.sciencedaily.com/releases/2017/07/170726131758.htm", "Matthew G. Costales, Yasumasa Matsumoto, Sai Pradeep Velagapudi, Matthew D. Disney. Small Molecule Targeted Recruitment of a Nuclease to RNA. Journal of the American Chemical Society, 2018; DOI: 10.1021/jacs.8b01233", "Scripps Research Institute. (2018, May 29). Novel RNA-modifying tool corrects genetic diseases. ScienceDaily. Retrieved November 15, 2018 from www.sciencedaily.com/releases/2018/05/180529153052.htm", "Lazzari, E. (2016, October 6). Don't shoot the messenger: How RNA could keep us young. Retrieved from https://theconversation.com/dont-shoot-the-messenger-how-rna-could-keep-us-young-65292"]}

RNA (Ribonucleic acid) is similar to DNA (Deoxyribonucleic acid). However, unlike DNA it is stable and move active member of nucleic acid family. Two major difference between RNA are 1) RNA differs from DNA by one nucleotide and 2) RNA consist of a single strand (one nucleotide) and not double helix. DNA and RNA are the most vital molecules in cell biology, responsible for storage and reading genetic information that is the base of all life. DNA encrypts all genetic information and is the prototype from which all biological life is created. RNA functions as the reader that decodes. There are three types of RNA 1) mRNA – copies fragments of genetic code, process called transcription, and transports to ribosomes, which are cellular factories that enables the production of proteins from this code. 2) tRNA – it is engaged for bringing amino acids, basic protein building blocks, to these protein factories, in response to the coded instructions received by mRNA. This protein building is called translation. 3) rRNA – is a component of the ribosome factory itself without which protein production cannot occur. Below are few techniques and applications from plenty of RNA applications.

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Keywords

Ribonucleic acid, RNA

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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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