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Data on uptake and metabolism of all 20 amino acids by Mycobacterium tuberculosis H37Rv (20 amino acids uptake.zip), shown in Figure 2. Data on kinetics of labelling on 15N-Asp (15N Asp.zip), shown in Figure 4g and h. Data on kinetics of labelling on 15N2-Asn (15N Asn.zip), shown in Figure 4g and h. Data on kinetics of labelling on 15N-Glu (15N Glu.zip), shown in Figure 4g and h. Data on kinetics of labelling on 15N2-Gln (15N Gln.zip), shown in Figure 4g and h. Data on kinetics of labelling on 15N-NH4+ (15N NH4+.zip), shown in Figure 4g and h. Data on position specific labelling with Asn and Gln (PIL.zip), shown in Figure 4b to f. Data on co-metabolism of Glu/Gln and Asp/Asn (co-metabolism.zip), shown in Figure 5.
This work was primarily supported by a Wellcome Trust New Investigator Award (104785/B/14/Z) to L.P.S.C. The L.P.S.C. lab is also funded by the Francis Crick Institute, which receives its core funding from Cancer Research UK (FC001060), the UK Medical Research Council (FC001060), and the Wellcome Trust (FC001060).
liquid chromatography mass spectrometry, Mycobacterium tuberculosis, metabolomics, nitrogen metabolism, stable isotope labelling
liquid chromatography mass spectrometry, Mycobacterium tuberculosis, metabolomics, nitrogen metabolism, stable isotope labelling
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