Diabetes Mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia. A good metabolic control can be achieved by appropriate drug therapy as well as strict diet control, periodical monitoring of blood glucose, and patient education regarding lifestyle modifications and drug therapy adherence. Pharmacists play a vital role in patient education. A Prospective Observational study was conducted for a period of 6 months at Rajiv Gandhi Institute of Medical Sciences on known T2DM patients, we aimed to assess the impact of patient counseling on the patient’s blood glucose levels. On daily basis patients who are visiting the general medicine department were screened as per the eligibility criteria after obtaining informed consent. At baseline all the subjects were assessed for their disease status along with the blood glucose levels and counseling was provided at monthly once for 3 months, finally the same data was assessed at the end of the study and compared. A total of 200 subjects were completed the study among them 130 (65%) were females, and 127 were in between 41-60 years. There is a statistical significant decrease was found in patient’s blood glucose levels and the average RBS, FBS, PPBS values of before and after patient counseling are (249.86 ± 37.702 Vs 199.71 ± 29.92), (150.47 ± 11.98 Vs 127.79 ± 10.47) and (161.61 ± 8.86 Vs 135.23 ± 7.18) respectively. With this study we conclude that clinical pharmacist’s education shown the significant improvement in controlling blood glucose levels and the management disease condition.